Often used for:
Treatment of HIV infection
What is atazanavir?
Atazanavir (Reyataz®) is a capsule used to treat infection caused by the human immunodeficiency virus (HIV). It belongs to a group of medicines known as protease inhibitors (PIs). Atazanavir can slow down how soon symptoms of HIV appear or slow the damage caused by HIV, but it cannot cure HIV infection. Capsules are available in 100 mg, 150 mg, 200 mg, and 300 mg strengths.
Atazanavir can block the enzyme UGT1A1, which helps remove bilirubin from the body. If bilirubin builds up, skin and eyes can turn yellow (jaundice). A genetic test can determine how well UGT1A1 works. Patients with slower UGT1A1 activity (such as those with Gilbert syndrome) may need to avoid atazanavir.
How to take atazanavir
- Take once daily as prescribed.
- Always take with food.
- Do not skip doses to maintain viral suppression.
Possible side effects
- Rash
- Feeling more tired than usual
- Low blood counts
- Headache
- Nausea
- High blood cholesterol levels
- High blood glucose levels
- Increased liver function tests
- Yellowing of the whites of the eyes
- Symptoms of an allergic reaction include: rash, hives, itching, chills, fever, headache, muscle ache, shortness of breath, coughing, tightness in the throat, swelling of the face or neck.
- Not all patients who take atazanavir will experience these side effects. Common side effects are in bold, but there may be others. Please report all suspected side effects to your doctor or pharmacist.
Tips for patients and families
- Be sure to discuss all questions and instructions with your doctor or pharmacist.
- Store capsules at room temperature away from heat and moisture.
- Keep all clinic appointments for blood tests to monitor blood counts and other lab values.
