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  • Main Shahrah-e-Faisal, Karachi.
  • Mon - Fri: 9.00am - 5.00pm
Often used for: Depression, anxiety, obsessive-compulsive disorder (OCD), panic disorder, post-traumatic stress disorder (PTSD)

What is paroxetine?

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant that increases serotonin levels in the brain to help regulate mood. It may be given in the clinic, hospital, or at home.

Paroxetine at home

  • Give in the morning at the same time each day.
  • May be taken with or without food; take with food if stomach upset occurs.
  • Swallow tablets and capsules whole unless instructed otherwise.
  • Shake oral liquid well and use the provided measuring device.
  • If a dose is missed, give it as soon as possible. If it is near the next dose, skip the missed dose. Do not double up.
  • Store at room temperature in a dry place away from bathrooms.
  • Do not use after the expiration date.
  • Follow safe handling, storage, and disposal instructions.

Possible side effects

  • Headache
  • Increased sweating
  • Constipation or diarrhea
  • Decreased appetite
  • Indigestion, nausea, or dry mouth
  • Sleepiness, tiredness, or weakness
  • Dizziness
  • Sleep problems
  • Tremors
  • Weight gain
  • Gas
  • Restlessness or nervousness
  • Back pain
  • Yawning
  • Eye problems (pain, vision changes, redness)
  • Growth problems
  • Fertility problems
  • Symptoms of an allergic reaction include rash, hives, itching, chills, fever, headache, muscle ache, shortness of breath, coughing, tightness in the throat, swelling of the face or neck
  • Not all patients will have these side effects. Report all symptoms to the health care provider.

Tips for patients and families

  • Discuss all questions and instructions with the health care provider or pharmacist.
  • It may take several weeks to see the full effects of paroxetine.
  • Contact the care team if symptoms worsen or do not improve.
  • Watch for mood or mental health changes including suicidal thoughts; seek immediate help if these occur.
  • Do not stop the medicine without medical guidance.
  • Avoid hazardous activities until you know how the medicine affects alertness.
  • Monitor weight and growth with regular checkups.
  • Report eye pain or vision changes promptly.
  • Let the care team know if the patient is sexually active, pregnant, or breastfeeding.