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Often used for: Various cancers including colorectal and liver cancers

What is regorafenib?

Regorafenib is an oral multikinase inhibitor that slows cancer growth and tumor blood vessel formation.

Possible side effects

  • Weight loss
  • Mouth irritation
  • Voice changes
  • Stomach pain
  • Muscle spasms
  • Hair loss
  • Serious reactions include allergic reactions, liver problems, neurological changes, bleeding, infection, heart rhythm changes, severe skin reactions, or wound-healing problems
  • Not all patients experience these effects. Report all symptoms.

Tips for patients and families

  • Discuss all instructions with the doctor or pharmacist.
  • Avoid grapefruit products.
  • Use effective birth control during treatment; do not take if pregnant or breastfeeding.
  • Handle tablets carefully and wash hands after touching.
  • Take with water after a low-fat meal at the same time each day.
  • Store at room temperature.