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Often used for: Leukemia, lymphoma, germ cell tumor, melanoma, sarcomas

What is vinblastine?

Vinblastine is an IV chemotherapy drug that can cause tissue damage if extravasated. It slows or stops cancer cell division and is often used with other medicines.

Possible long-term effects

  • Peripheral neuropathy

Possible side effects

  • Constipation or abdominal pain
  • Jaw pain
  • Difficulty walking
  • Numbness or tingling in hands or feet
  • Muscle pain or weakness
  • Bone or joint pain
  • Nausea or vomiting
  • Loss of appetite
  • Pain when urinating
  • Vision changes
  • Dizziness
  • Low blood counts
  • Hair loss
  • Low sodium levels
  • Skin irritation at the IV site
  • Not all patients experience these effects. Report all symptoms.

Tips for families

  • Discuss instructions with the care team.
  • A stool softener or laxative may be recommended.
  • Report numbness, tingling, or nerve pain.
  • Avoid grapefruit or Seville orange products.
  • Use birth control during treatment and for 6 months afterward.
  • Inform the doctor if pregnant or breastfeeding.
  • Follow safe handling instructions; avoid contact with body fluids for 48 hours after dosing.